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News and Announcements, Press Releases, Research Stories, Second Century Initiative

Georgia State University Neuroscientists to Investigate Neural Markers of Mental Illness

Georgia State University Neuroscientists to Investigate Neural Markers of Mental Illness

Neuroscientists at Georgia State University are using large-scale imaging analysis to study how symptoms associated with schizophrenia, bipolar disorder and major depression relate to changes in the brain. The researchers say they hope to yield new diagnostic classifications, uncover potential new treatment targets in the brain and identify which patients may benefit from those treatments.

The team, led by the Second Century Initiative’s Jessica Turner, professor of psychology and neuroscience, and Vince Calhoun, Distinguished University Professor of Psychology and director of the Center for Translational Research in Neuroimaging and Data Science (TReNDS), will examine two so-called “negative” symptoms, anhedonia (loss of pleasure) and asociality (loss of interest in social engagement), in patients with schizophrenia, major depression and bipolar disorder. The work is supported by a five-year, $5 million grant from the National Institute of Mental Health (NIMH).

Faculty Profiles, Feature Stories, News and Announcements

2CI Faculty Q&A: Nancy Forger

2CI Faculty Q&A: Nancy Forger

The Second Century Initiative (2CI) brought more than 80 leading scholars and researchers across a diverse array of disciplines; its successor program, the Next Generation Program, continues to do so. Each faculty member has provided the university with their unique perspectives and leadership in their fields. Their work moves forward important and innovative research and scholarship, while lifting the reputation of Georgia State University and its colleges/schools for work addressing the challenges of the 21st century.

This article is part of a series highlighting individual faculty members and their perspectives through a question-and-answer format. Dr. Nancy G. Forger is a Professor and Director of the Neuroscience Institute, and was recruited to Georgia State as part of 2CI’s second round. The Neuroscience Institute at Georgia State celebrated its 10th anniversary in 2018.

Feature Stories, News and Announcements, Research Stories, Second Century Initiative

A 2CI Scientist’s International Collaboration and a Neuroscience Breakthrough: How the Brain Controls Flexible Learning

A 2CI Scientist’s International Collaboration and a Neuroscience Breakthrough: How the Brain Controls Flexible Learning

A Second Century Initiative researcher at Georgia State University is a member of an international team of scientists who have made an important breakthrough in understanding the mechanisms in the brain that control cognitive flexibility.

Dr. Angela M. Mabb, a 2CI faculty member at Georgia State, collaborated with researchers at the University of Bradford and the University of Warwick in the United Kingdom. Their results were published in the Cell Press journal Neuron.

The study highlights the importance of a protein known as Arc in learning and memory and shows that proteins not only need to be switched on, but also need to be removed at the correct times for proper learning. More important, these findings show for the first time that the dynamic expression of a single protein has profound implications in replacing a previously learned task with a new one.